adenosine deaminase deficiency

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adenosine deaminase deficiency (ADA deficiency) (dee-am-in-ayz) n. a genetic disorder characterized by a defect in the enzyme adenosine deaminase (ADA), which is involved in purine metabolism. Deficiency of this enzyme results in damage to the antibody-producing lymphocytes, which leads to severe combined immune deficiency (SCID).

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