Kupffer cells Specialized macrophages that dispose of old blood cells and particulate matter. Kupffer cells, named after Karl Wilhelm von Kupffer (1829–1902), are found in the bloodstream and in the liver, attached to the walls of the sinusoids.

Kupffer cells (kuup-fer) pl. n. phagocytic cells that line the sinusoids of the liver (see macrophage). They are particularly concerned with the formation of bile. [ K. W. von Kupffer (1829–1902), German anatomist]