Clarke, Patricia Hannah (1919–)
Clarke, Patricia Hannah (1919–)
Welsh biochemist. Name variations: Patricia Green; Patricia Hannah Green. Born Patricia Hannah Green, July 29, 1919, in Pontypridd, Wales; m. Michael Clarke, 1940; children: 2 (born 1947 and 1949).
Attended Howells School in Wales on scholarship and Girton College in Cambridge as a Sparke scholar; employed in war work, testing explosives in Woolwich and Swansea Arsenal; joined B.C.J.G. Knight at Wellcome Research Laboratories in Beckenham, Kent (1944–47) to work on Clostridia (pathogenic) immunization methods (research results were later published in Journal of General Microbiology, 1947); worked with S.T. Cowan at National Collection of Type Cultures to establish micromethods to identify bacteria based on enzyme reactions (1951–53); employed as lecturer (1953–66), as reader (1966–74), and as microbial biochemistry professor (1974–84) at University College in London; revealed illuminating research results on synthesis of permeases and novel enzymes and later on mechanism of gene regulation. Elected as fellow (1976), council member, and vice president (1981–82) to Royal Society.