NAICS 325414 - Biological Product (Except Diagnostic) Manufacturing

GENERAL STATISTICS
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: 1992, 1997, 2002 Economic Census; other years, up to 2006, are from the Annual Survey of Manufactures. Establishment counts for non-Census years are from County Business Patterns; 1997 and 2002 values are from the 1997 and 2002 censuses respectively, reported in the Federal Government's NAICS format. Other years were originally reported in equivalent SIC format. ‘P’s show projections by the editors.
1991		248	127	12.1	6.4	12.1	391.5	11.00	962.4	1,483.3	2,405.6	108.3
1992	193	275	140	18.4	8.0	15.1	627.2	12.48	1,313.5	2,754.6	3,974.0	294.3
1993		296	137	19.0	9.2	18.1	732.5	12.57	1,483.2	3,479.3	4,914.0	405.1
1994		286	142	19.8	9.9	18.6	788.3	13.81	1,570.3	3,829.9	5,310.2	360.6
1995		284	117	21.1	11.0	20.4	854.5	13.74	1,719.2	4,564.3	6,226.6	452.7
1996		277	107	19.6	9.7	19.1	865.5	14.06	1,713.2	4,661.5	6,402.0	359.5
1997	268	364	172	23.3	12.1	25.0	1,020.1	15.72	2,134.0	3,728.9	5,685.9	426.9
1998		347	158	24.1	12.2	24.6	1,096.6	16.90	2,257.6	3,898.3	6,056.8	390.0
1999		358	155	21.2	11.4	22.8	958.0	18.15	2,272.6	3,711.7	5,798.6	371.8
2000		356	153	22.8	11.8	26.5	1,114.1	15.74	2,726.5	4,257.3	6,827.5	570.7
2001		358	144	24.0	11.9	27.1	1,207.1	16.35	2,866.3	4,810.4	7,521.5	620.0
2002	229	296	130	22.9	11.3	21.8	1,225.8	21.96	2,550.9	5,610.0	7,790.7	547.5
2003		330	193	23.5	11.7	23.5	1,319.5	22.47	2,733.8	6,549.4	9,176.3	553.9
2004		320	179	22.4	11.2	22.3	1,327.3	24.64	2,593.5	7,439.2	9,847.8	548.2
2005		319	183	22.7	11.3	22.3	1,341.1	25.48	3,154.0	8,936.7	11,983.2	645.0
2006		353P	178P	25.4	11.9	23.8	1,657.0	27.89	4,645.7	11,506.2	16,275.2	714.5
2007		358P	182P	25.8P	12.9P	26.6P	1,583.3P	26.48P	3,574.9P	8,854.2P	12,524.0P	702.4P
2008		363P	185P	26.4P	13.1P	27.2P	1,648.1P	27.51P	3,751.6P	9,291.9P	13,143.1P	730.8P
2009		367P	189P	26.9P	13.4P	27.8P	1,712.9P	28.55P	3,928.3P	9,729.5P	13,762.1P	759.3P
2010		372P	193P	27.4P	13.6P	28.4P	1,777.6P	29.58P	4,105.0P	10,167.1P	14,381.1P	787.7P

INDICES OF CHANGE
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: Same as General Statistics. Values reflect change from the base year, 2002. Values above 100 mean greater than 2002, values below 100 mean less than 2002, and the values of 100 in other years means same as 2002. ‘P’s show projections by the editors.
1992	84	93	108	80	71	69	51	57	51	49	51	54
1997	117	123	132	102	107	115	83	72	84	66	73	78
2001		121	111	105	105	124	98	74	112	86	97	113
2002	100	100	100	100	100	100	100	100	100	100	100	100
2003		111	148	103	104	108	108	102	107	117	118	101
2004		108	138	98	99	102	108	112	102	133	126	100
2005		108	141	99	100	102	109	116	124	159	154	118
2006		119P	137P	111	105	109	135	127	182	205	209	131
2007		121P	140P	113P	114P	122P	129P	121P	140P	158P	161P	128P
2008		122P	143P	115P	116P	125P	134P	125P	147P	166P	169P	133P
2009		124P	145P	117P	119P	128P	140P	130P	154P	173P	177P	139P
2010		126P	148P	120P	120P	130P	145P	135P	161P	181P	185P	144P

SELECTED RATIOS
For 2002	Avg. of All Manufact.	Analyzed Industry	Index	For 2002	Avg. of All Manufact.	Analyzed Industry	Index
Sources: Same as General Statistics. The ‘Average of All Manufacturing’ column represents the average of all manufacturing industries reported for the most recent complete year available. The Index shows the relationship between the Average and the Analyzed Industry. For example, 100 means that they are equal; 500 that the Analyzed Industry is five times the average; 50 means that the Analyzed Industry is half the national average. The abbreviation ‘na’ is used to show that data are ‘not available’. Ratios shown for 2002, the last complete census year.
Employees per Establishment	42	77	184	Value Added per Production Worker	182,367	496,460	272
Payroll per Establishment	1,639,184	4,141,216	253	Cost per Establishment	5,769,015	8,617,905	149
Payroll per Employee	39,053	53,528	137	Cost per Employee	137,446	111,393	81
Production Workers per Establishment	30	38	129	Cost per Production Worker	195,506	225,743	115
Wages per Establishment	694,845	1,617,324	233	Shipments per Establishment	11,158,348	26,319,932	236
Wages per Production Worker	23,548	42,365	180	Shipments per Employee	265,847	340,205	128
Hours per Production Worker	1,980	1,929	97	Shipments per Production Worker	378,144	689,442	182
Wages per Hour	11.89	21.96	185	Investment per Establishment	361,338	1,849,662	512
Value Added per Establishment	5,381,325	18,952,703	352	Investment per Employee	8,609	23,908	278
Value Added per Employee	128,210	244,978	191	Investment per Production Worker	12,245	48,451	396

LEADING COMPANIES Number shown: 75 Total sales ($ mil): 94,476 Total employment (000): 216.8
Company Name	Address				CEO Name	Phone	Co. Type	Sales ($ mil)	Empl. (000)
Source: Ward's Business Directory of U.S. Private and Public Companies, Volumes 1 and 2, 2008. The company type code used is as follows: P - Public, R - Private, S - Subsidiary, D - Division, J - Joint Venture, A - Affiliate, G - Group. Sales are in millions of dollars, employees are in thousands. An asterisk (*) indicates an estimated sales volume. The symbol < stands for ‘less than’. Company names and addresses are truncated, in some cases, to fit into the available space.
Merck and Company Inc.	PO Box 100	Whitehouse Sta	NJ	08889	David Anstice	908-423-1000	P	24,198	59.8
Amgen Inc.	1 Amgen Center Dr.	Thousand Oaks	CA	91320		805-447-1000	P	14,771	21.0
Baxter International Inc.	1 Baxter Pky.	Deerfield	IL	60015		847-948-2000	P	11,263	46.0
Genentech Inc.	1 DNA Way	S San Francisco	CA	94080		650-225-1000	P	9,443	10.5
Monsanto Co.	800 N Lindbergh	St. Louis	MO	63167		314-694-1000	P	8,563	18.8
Pasteur Merieux Connaught Labs	PO Box 187	Swiftwater	PA	18370	Michel Greco	570-839-7187	S	5,342*	9.0
Gilead Sciences Inc.	333 Lakeside Dr.	Foster City	CA	94404		650-574-3000	P	4,230	3.0
Genzyme Corp.	500 Kendall St.	Cambridge	MA	02142		617-252-7500	P	3,458	10.0
Biogen Idec Inc.	14 Cambridge Ctr.	Cambridge	MA	02142	James C. Mullen	617-679-2000	P	2,137	4.3
Arkema Inc.	2000 Market St.	Philadelphia	PA	19103	Thierry Le Henaff	215-419-7000	S	1,600*	2.6
Invitrogen Corp.	PO Box 6482	Carlsbad	CA	92008		760-603-7200	P	1,282	4.3
Charles River Labs Int’l	251 Ballardvale St.	Wilmington	MA	01887	James C. Foster	978-658-6000	P	1,231	8.5
Talecris Biotherapeutics Hold.	4101 Resrch Cmns	Research Tri Pk	NC	27709	Lawrence D. Stern	919-316-6300	R	1,115	3.5
Boehringer Ingelheim Vetmedica	2621 N Belt Hwy.	Saint Joseph	MO	64506	George Heidgerken	816-233-2571	S	897*	0.3
ImClone Systems Inc.	180 Varick St.	New York	NY	10014	Alexander Denner	212-645-1405	P	591	1.0
Integra LifeSciences Holdings	311 Enterprise Dr.	Plainsboro	NJ	08536		609-275-0500	P	419	1.8
PDL BioPharma Inc.	1400 Seaport Blvd.	Redwood City	CA	94063	L. Patrick Gage	650-454-1000	P	415	1.1
Twin Laboratories Inc.	150 Motor Pky.	Hauppauge	NY	11788	Ross Blechman	631-467-3140	R	398*	0.7
Martek Biosciences Corp.	6480 Dobbin Rd.	Columbia	MD	21045	Steve Dubin	410-740-0081	P	307	0.5
Enzon Pharmaceuticals Inc.	685 Rte. 202/206	Bridgewater	NJ	08807	Jeffrey H. Buchalter	908-541-8600	P	186	0.4
American Peptide Company Inc.	777 E Evelyn Ave.	Sunnyvale	CA	94086	Kenichi Ito	408-733-7604	R	134*	<0.1
MedImmune Vaccines Inc.	319 N Bernardo	Mountain View	CA	94043	David M. Mott	650-603-2000	S	127*	0.5
Meridian Bioscience Inc.	3471 River Hills Dr	Cincinnati	OH	45244		513-271-3700	P	123	0.4
Osteotech Inc.	51 James Way	Eatontown	NJ	07724		732-542-2800	P	104	0.3
Intervet Inc.	PO Box 318	Millsboro	DE	19966	Klaus Olbers	302-934-8051	S	103*	0.5
Stratagene Cloning Systems	11011 N Torrey Pine	La Jolla	CA	92037	Joseph A. Sorge	858-373-6300	P	96	0.5
Rigel Pharmaceuticals Inc.	1180 Veterans Blvd.	S San Francisco	CA	94080	James M. Gower	650-624-1100	P	92	0.2
Nabi Biopharmaceuticals	12276 Wilkins Ave.	Rockville	MD	20852		301-770-3099	P	90	0.7
NPS Pharmaceuticals Inc.	383 Colorow Dr.	Salt Lake City	UT	84108	N. Anthony Coles	801-583-4939	P	86	<0.1
Research & Diagnostic Systems	614 McKinley NE	Minneapolis	MN	55413	Thomas E. Oland	612-379-2956	S	86*	0.6
CV Therapeutics Inc.	3172 Porter Dr.	Palo Alto	CA	94304		650-384-8500	P	83	0.5
Heska Corp.	3760 Rocky Mtn	Loveland	CO	80538		970-493-7272	P	82	0.3
Clontech Laboratories Inc.	1290 Terra Bella Av	Mountain View	CA	94043	Deborah J. Neff	650-919-7300	S	71*	0.3
LifeCore Biomedical Inc.	3515 Lyman Blvd.	Chaska	MN	55318	Dennis J. Allingham	952-368-4300	P	70	0.2
Irvine Scientific Sales Co.	2511 Daimler St.	Santa Ana	CA	92705	Michael Kelly	949-261-7800	R	65*	<0.1
Antigenics Inc.	3 Forbes Rd.	Lexington	MA	02421	Garo H. Armen	781-674-4400	S	64*	0.3
Diamond Animal Health Inc.	2538 SE 43rd St.	Des Moines	IA	50327		515-263-8600	S	58*	0.1
Embrex Inc.	PO Box 13989	Research Tri Pk	NC	27709		919-941-5185	S	53	0.3
Hardy Media Inc.	1430 W McCoy Ln.	Santa Maria	CA	93455	Jay Hardy	805-346-2766	R	51*	0.1
Alnylam Pharmaceuticals Inc.	300 3rd St., 3rd Fl	Cambridge	MA	02142		617-551-8200	P	51	0.1
Trimeris Inc.	3500 Paramount	Morrisville	NC	27560	Richard Crout	919-419-6050	P	49	<0.1
BioForm Medical Inc.	1875 S Grant St.	San Mateo	CA	94402	Steven L. Basta	650-286-4000	P	47	0.3
Fujirebio Diagnostics Inc.	201 Great Vly Pky.	Malvern	PA	19355	Takeo Hayashi	610-240-3800	S	46*	0.1
Affymax Inc.	4001 Miranda Ave.	Palo Alto	CA	94304	Arlene M. Morris	650-812-8700	P	44	0.2
Nutrition 21 Inc.	4 Manhattanville Rd	Purchase	NY	10577	John H. Gutfreund	914-701-4500	P	42	<0.1
ZymoGenetics Inc.	1201 Eastlake Ave.	Seattle	WA	98102	Bruce L.A. Carter	206-442-6600	P	39	0.6
Covance Research Products Inc.	PO Box 7200	Denver	PA	17517		717-336-4921	S	38*	0.2
Sigma-Genosys	1442 Lk Front Cir.	The Woodlands	TX	77380		281-363-3693	S	36*	0.2
Encysive Pharmaceuticals Inc.	4848 Loop Central	Houston	TX	77081	Ron Anderson	713-796-8822	P	36	0.1
Research Seeds Inc.	PO Box 339	Nampa	ID	83653	Mark McCaslin	208-466-3568	R	33*	<0.1
Biomune Co.	8901 Rosehill Rd.	Shawnee Msn	KS	66215		913-894-0230	R	33*	<0.1
Anika Therapeutics Inc.	32 Wiggins Ave.	Bedford	MA	01730		781-457-9000	P	31	<0.1
Worthington Bio Chemical Corp.	730 Vassar Ave.	Lakewood	NJ	08701	Von Worthington	732-942-1660	R	29*	<0.1
Santa Cruz Biotechnology Inc.	2145 Delaware Ave.	Santa Cruz	CA	95060	John Stephenson	831-457-3800	R	28*	0.1
PML Microbiologicals Inc.	27120 SW 95th Ave.	Wilsonville	OR	97070	Charlie Mamrak	503-570-2500	S	28*	0.1
Targacept Inc.	200 E First St.	Winston-Salem	NC	27101		336-480-2100	P	28	<0.1
Intarcia Therapeutics Inc.	2000 Powell St.	Emeryville	CA	94608	K. Alice Leung	510-652-2600	R	27*	<0.1
Accentia BioPharmaceuticals	324 S Hyde Park	Tampa	FL	33606	Steven R. Arikian	813-864-2554	P	25	0.3
Microban Products Co.	11515 Vanstory Dr.	Huntersville	NC	28078	William Rubinstein	704-875-0806	R	25*	<0.1
International Immunology Corp.	25549 Adams Ave.	Murrieta	CA	92562	Shunsaku Shibota	951-677-5629	R	25*	<0.1
Seattle Genetics Inc.	21823 30th Dr. SE	Bothell	WA	98021		425-527-4000	P	22	0.2
Momenta Pharmaceuticals Inc.	675 West Kendall St	Cambridge	MA	02142		617-491-9700	P	22	0.2
Trubion Pharmaceuticals Inc.	2401 4th Ave., 1050	Seattle	WA	98121	Peter A. Thompson	206-838-0500	P	20	<0.1
ImmunoVision Inc.	1820 Ford Ave.	Springdale	AR	72764	Giorgio D’Urso		S	20*	<0.1
MML Diagnostics Packaging Inc.	PO Box 458	Troutdale	OR	97060	Dale Pestes	503-666-8398	R	19*	<0.1
Bachem Inc.	3132 Kashiwa St.	Torrance	CA	90505	Phillip Ottiger	310-539-4171	R	18*	<0.1
Neurobiological Technologies	2000 Powell St.	Emeryville	CA	94608	Abraham E. Cohen	510-595-6000	P	18	<0.1
Curis Inc.	45 Moulton St.	Cambridge	MA	02138	James McNab	617-503-6500	P	16	<0.1
North American Scientific Inc.	20200 Sunburst St.	Chatsworth	CA	91311	Irwin Gruverman	818-734-8600	P	15	<0.1
Vical Inc.	10390 Pac. Cntr Ct	San Diego	CA	92121		858-646-1100	P	15	0.1
Antibodies Inc.	PO Box 1560	Davis	CA	95617	Richard Krogsrud	530-758-4400	R	15*	<0.1
Palatin Technologies Inc.	4-C Cedar Brook Dr.	Cranbury	NJ	08512	John K.A. Prendergast	609-495-2200	P	14	<0.1
Repligen Corp.	41 Seyon St. Bldg 1	Waltham	MA	02453	Walter C. Herlihy	781-250-0111	P	14	<0.1
GTC Biotherapeutics Inc.	175 Crossing Blvd.	Framingham	MA	01702	Geoffrey F. Cox	508-620-9700	P	14	0.2
Cypress Bioscience Inc.	4350 Executive Dr.	San Diego	CA	92121		858-452-2323	P	14	<0.1

MATERIALS CONSUMED
Material	Quantity	Delivered Cost ($ million)
Source: 2002 Economic Census. Explanation of symbols used: (D): Withheld to avoid disclosure of competitive data; na: Not available; (S): Withheld because statistical norms were not met; (X): Not applicable; (Z): Less than half the unit shown; nec: Not elsewhere classified; nsk: Not specified by kind; - : zero; p : 10–19 percent estimated; q : 20–29 percent estimated.
Antibiotics (bulk), for human and veterinary use	(X)	29.1
Antibiotics (bulk), for animal feeds	(X)	(D)
Vitamins, natural and synthetic, human and veterinary use (bulk)	(X)	(D)
Vitamins, natural and synthetic, for animal feeds (bulk)	(X)	(D)
Agricultural products, crude (incl. flowers, grains, seeds, herbs, etc.)	(X)	14.7
Processed food and kindred products (lactose, meat packing plant products, yeast, etc.)	(X)	6.0
Blood derivatives and extenders	(X)	875.9
All other bulk medicinal and botanical uncompounded drugs	(X)	82.5
Gelatin (pharmaceutical grade) and gelatin capsules	(X)	(D)
Alcohols, excluding ethyl (100 percent basis)	(X)	2.4
Cyclic crudes and intermediates (including organic colors)	(X)	(D)
Other synthetic organic chemicals	(X)	41.1
Fabricated plastics products (excluding containers)	(X)	19.3
Metal closures and crowns for containers	(X)	3.0
Labels, coupons, instructions, and other printed material	(X)	15.1
Plastics containers	(X)	26.0
Glass containers	(X)	21.9
Metal containers	(X)	(D)
Paperboard containers, boxes, and corrugated paperboard	(X)	12.0
All other materials, components, parts, containers, and supplies	(X)	420.3
Materials, ingredients, containers, and supplies, nsk	(X)	252.6

PRODUCT SHARE DETAILS
Product or Product Class Shipments	Mil. $	Product or Product Class Shipments	Mil. $
Source: 2002 Economic Census. The values are product shipments in millions of dollars for 2002. Total product shipments may be lower or higher than industry shipments. See Introduction for a full discussion. Values of indented subcategories are summed in the main heading(s). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. The abbreviation nsk stands for ‘not specified by kind’ and nec for ‘not elsewhere classified’. A dash (-) means zero.
BIOLOGICAL PRODUCTS, EXCEPT DIAGNOSTICS	8,540.2	industrial, and other uses, nec	1,731.4
Blood and blood derivatives, for human use	1,388.1	Biological veterinary vaccines, bacterins, toxoids, other antigens, and other biological products	917.5
Biological products, blood and blood derivatives, for human use	1,387.7	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, veterinary vaccines, including vaccines against foot-and-mouth disease	585.6
Biological products, diagnostic, blood and blood derivatives, human blood plasma, for human use	953.7	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, bacterins, toxoids, and other antigens, except allergens, for active immunization	65.0
Biological products, except diagnostic, blood and blood derivatives, other blood and blood derivatives or fractions, except those used for passive immunization	434.0	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, other biological products, including veterinary blood derivatives, antitoxins, immune serums, and allergens, except diagnostics	266.9
Blood and blood derivatives, for human use, nsk	0.3	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, biological products for industrial and other uses, except culture media	679.2
Vaccines, toxoids, and antigens, except allergens, for human use	3,015.3	Biological products for industrial and all other miscellaneous uses, non-diagnostic culture media	95.1
Other biologics, except diagnostic, for human use	2,165.2	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, nsk	39.7
Biological products, except diagnostic, for human use	2,165.2	Biological products, except diagnostics, nsk, total	240.2
Biological products, except diagnostic, other biologics, antitoxins, antivenoms, immune globulins, therapeutic immune serums, etc., for therapeutic use and passive immunization	2,052.4
Biological products, except diagnostic, other biologics, allergenic extracts and other biologics for human use, including poison ivy and oak extracts, except diagnostic allergens	112.8
Biological products, except diagnostic, for veterinary ,

INPUTS AND OUTPUTS FOR BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Compensation of employees	20.9		Pharmaceutical preparations	23.6	Manufg.
Management of companies & enterprises	15.3	Services	Exports of goods & services	12.8	Cap Inv
Biological products (except diagnostic)	13.2	Manufg.	Medicinal & botanical manufacturing	12.0	Manufg.
Wholesale trade	8.6	Trade	Biological products (except diagnostic)	11.2	Manufg.
Scientific research & development services	5.4	Services	Physician, dentist, other health practitioner offices	9.5	Services
Pharmaceutical preparations	2.9	Manufg.	Medical & diagnostic labs & outpatient services	6.2	Services
Medicinal & botanical manufacturing	1.3	Manufg.	In-vitro diagnostic substances	4.7	Manufg.
Management, scientific, & technical consulting	1.2	Services	Change in private inventories	4.6	In House
Advertising & related services	1.2	Services	Cattle	2.0	Agric.
Noncomparable imports	1.1	Foreign	General Federal government services, nondefense	1.9	Fed Govt
Power generation & supply	0.7	Util.	Agriculture & forestry services	1.8	Agric.
Real estate	0.6	Fin/R.E.	Veterinary services	1.5	Services

INPUTS AND OUTPUTS FOR BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING - Continued
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Source: Benchmark Input-Output Accounts for the U.S. Economy, 2002, U.S. Department of Commerce, Washington, D.C., January 2008. The abbreviation nec stands for ‘not elsewhere classified’.
Basic organic chemicals, nec	0.5	Manufg.	Poultry & eggs	1.3	Agric.
Truck transportation	0.4	Util.	Nursing & residential care facilities	0.9	Services
Plastics products, nec	0.4	Manufg.	Amusement parks, arcades, & gambling	0.9	Services
Taxes on production & imports, less subsidies	0.3		Retail trade	0.8	Trade
Lessors of nonfinancial assets	0.3	Fin/R.E.	General S/L govt. services	0.7	S/L Govt
Maintenance/repair of nonresidential structures	0.3	Construct.	Individual & family services	0.7	Services
Services to buildings & dwellings	0.2	Services	Architectural, engineering, & related services	0.5	Services
Business support services	0.2	Services	Community food, housing, relief, & rehabilitation	0.5	Services
Telecommunications	0.2	Services	Museums, historical sites, zoos, & parks	0.5	Services
Warehousing & storage	0.2	Util.	Scientific research & development services	0.4	Services
In-vitro diagnostic substances	0.2	Manufg.	Maintenance/repair of nonresidential structures	0.3	Construct.
Legal services	0.2	Services	Other S/L govt. enterprises	0.2	S/L Govt
Automotive equipment rental & leasing	0.2	Fin/R.E.	Wood containers & pallets	0.1	Manufg.
Employment services	0.2	Services	Hospitals	0.1	Services
Printing	0.2	Manufg.	Personal services, nec	0.1	Services
Automotive repair & maintenance, ex. car washes	0.2	Services
Animal, except poultry, processing	0.2	Manufg.
Chemical products & preparations, nec	0.2	Manufg.
Glass containers	0.2	Manufg.
Commercial & industrial equipment repair/maintenance	0.2	Services
Environmental & other technical consulting services	0.1	Services
Petroleum refineries	0.1	Manufg.
Paperboard containers	0.1	Manufg.
Office administrative services	0.1	Services
Natural gas distribution	0.1	Util.
Data processing, hosting, & related services	0.1	Services
Waste management & remediation services	0.1	Services
Specialized design services	0.1	Services

OCCUPATIONS EMPLOYED BY PHARMACEUTICAL & MEDICINE MANUFACTURING
Occupation	% of Total 2006	Change to 2016	Occupation	% of Total 2006	Change to 2016
Source: Industry-Occupation Matrix, Bureau of Labor Statistics, December 4, 2007. These data are reported based on 4-digit NAICS categories but have been matched to corresponding 6-digit NAICS industry codes. The change reported for each occupation to the year 2016 is a percent of growth or decline as estimated by the Bureau of Labor Statistics. The abbreviation nec stands for ‘not elsewhere classified’.
Packaging & filling machine operators & tenders	7.0	13.4	General & operations managers	1.6	13.4
Chemists	5.2	13.4	Biochemists & biophysicists	1.4	26.0
Mixing & blending machine operators & tenders	3.6	26.0	Machine feeders & offbearers	1.4	13.4
Chemical equipment operators & tenders	3.5	26.0	Packers & packagers, hand	1.4	0.8
Medical scientists, exc epidemiologists	3.4	26.0	Shipping, receiving, & traffic clerks	1.4	21.3
Inspectors, testers, sorters, samplers, & weighers	3.0	18.8	Customer service representatives	1.4	38.6
First-line supervisors/managers of production workers	2.6	26.0	Secretaries, exc legal, medical, & executive	1.3	12.1
Biological technicians	2.5	26.0	Industrial production managers	1.3	26.0
Chemical technicians	2.3	26.0	Managers, nec	1.3	26.0
Maintenance & repair workers, general	2.1	26.0	Production workers, nec	1.2	23.7
Sales representatives, wholesale & manufacturing, tech	2.0	26.0	Office clerks, general	1.2	24.2
Separating, precipitating, & still machine operators	1.9	26.0	Microbiologists	1.1	26.0
Business operation specialists, nec	1.8	38.6	Industrial machinery mechanics	1.1	44.9
Executive secretaries & administrative assistants	1.7	26.0	Accountants & auditors	1.1	26.0
Team assemblers	1.7	26.0	Natural sciences managers	1.1	26.0
Laborers & freight, stock, & material movers, hand	1.6	13.4	Production, planning, & expediting clerks	1.1	26.0

INDUSTRY DATA BY STATE
State	Establishments	Shipments				Employment			Cost as % of Shipments	Investment per Employee ($)
State	Establishments	Total ($ mil)	% of U.S.	Per Establ.	Total Number	% of U.S.	Per Establ.	Wages ($/hour)	Cost as % of Shipments	Investment per Employee ($)
Source: 2002 Economic Census. The states are in descending order of shipments or establishments (if shipment data are missing for the majority). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. States marked with (D) are sorted by number of establishments. A dash (-) indicates that the data element cannot be calculated. Data may not show all states active in the NAICS category. All data available at the time of publication are shown.
North Carolina	12	1,356.0	17.4	113,001.1	2,983	13.1	249	20.49	37.9	43,215
California	45	1,109.9	14.2	24,664.7	4,281	18.7	95	27.49	44.2	21,788
Maryland	13	835.3	10.7	64,253.3	1,029	4.5	79	21.76	7.8	13,920
Massachusetts	15	803.6	10.3	53,572.6	1,334	5.8	89	23.13	9.4	27,343
Iowa	11	444.0	5.7	40,364.3	1,713	7.5	156	12.88	33.4	12,640
Wisconsin	10	198.0	2.5	19,803.1	932	4.1	93	23.36	28.0	10,558
New York	6	132.6	1.7	22,103.0	434	1.9	72	23.19	42.4	8,763
Georgia	8	124.9	1.6	15,614.9	434	1.9	54	15.97	26.9	25,477
Texas	24	88.6	1.1	3,693.0	512	2.2	21	19.15	22.9	10,219
Missouri	10	81.5	1.0	8,149.7	529	2.3	53	18.44	25.9	14,439
Nebraska	7	80.7	1.0	11,532.6	448	2.0	64	18.84	36.0	28,857
Kansas	7	54.9	0.7	7,836.0	257	1.1	37	15.71	31.0	10,354
Minnesota	9	30.7	0.4	3,415.2	172	0.8	19	19.36	31.2	11,390
Maine	7	27.6	0.4	3,940.0	120	0.5	17	13.12	41.6	46,700
Florida	7	20.5	0.3	2,922.7	113	0.5	16	15.46	24.9	3,894

NAICS 325414 - Biological Product (Except Diagnostic) Manufacturing

GENERAL STATISTICS
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: 1992, 1997, 2002 Economic Census; other years, up to 2006, are from the Annual Survey of Manufactures. Establishment counts for non-Census years are from County Business Patterns; 1997 and 2002 values are from the 1997 and 2002 censuses respectively, reported in the Federal Government's NAICS format. Other years were originally reported in equivalent SIC format. ‘P’s show projections by the editors.
1991		248	127	12.1	6.4	12.1	391.5	11.00	962.4	1,483.3	2,405.6	108.3
1992	193	275	140	18.4	8.0	15.1	627.2	12.48	1,313.5	2,754.6	3,974.0	294.3
1993		296	137	19.0	9.2	18.1	732.5	12.57	1,483.2	3,479.3	4,914.0	405.1
1994		286	142	19.8	9.9	18.6	788.3	13.81	1,570.3	3,829.9	5,310.2	360.6
1995		284	117	21.1	11.0	20.4	854.5	13.74	1,719.2	4,564.3	6,226.6	452.7
1996		277	107	19.6	9.7	19.1	865.5	14.06	1,713.2	4,661.5	6,402.0	359.5
1997	268	364	172	23.3	12.1	25.0	1,020.1	15.72	2,134.0	3,728.9	5,685.9	426.9
1998		347	158	24.1	12.2	24.6	1,096.6	16.90	2,257.6	3,898.3	6,056.8	390.0
1999		358	155	21.2	11.4	22.8	958.0	18.15	2,272.6	3,711.7	5,798.6	371.8
2000		356	153	22.8	11.8	26.5	1,114.1	15.74	2,726.5	4,257.3	6,827.5	570.7
2001		358	144	24.0	11.9	27.1	1,207.1	16.35	2,866.3	4,810.4	7,521.5	620.0
2002	229	296	130	22.9	11.3	21.8	1,225.8	21.96	2,550.9	5,610.0	7,790.7	547.5
2003		330	193	23.5	11.7	23.5	1,319.5	22.47	2,733.8	6,549.4	9,176.3	553.9
2004		320	179	22.4	11.2	22.3	1,327.3	24.64	2,593.5	7,439.2	9,847.8	548.2
2005		319	183	22.7	11.3	22.3	1,341.1	25.48	3,154.0	8,936.7	11,983.2	645.0
2006		353P	178P	25.4	11.9	23.8	1,657.0	27.89	4,645.7	11,506.2	16,275.2	714.5
2007		358P	182P	25.8P	12.9P	26.6P	1,583.3P	26.48P	3,574.9P	8,854.2P	12,524.0P	702.4P
2008		363P	185P	26.4P	13.1P	27.2P	1,648.1P	27.51P	3,751.6P	9,291.9P	13,143.1P	730.8P
2009		367P	189P	26.9P	13.4P	27.8P	1,712.9P	28.55P	3,928.3P	9,729.5P	13,762.1P	759.3P
2010		372P	193P	27.4P	13.6P	28.4P	1,777.6P	29.58P	4,105.0P	10,167.1P	14,381.1P	787.7P

INDICES OF CHANGE
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: Same as General Statistics. Values reflect change from the base year, 2002. Values above 100 mean greater than 2002, values below 100 mean less than 2002, and the values of 100 in other years means same as 2002. ‘P’s show projections by the editors.
1992	84	93	108	80	71	69	51	57	51	49	51	54
1997	117	123	132	102	107	115	83	72	84	66	73	78
2001		121	111	105	105	124	98	74	112	86	97	113
2002	100	100	100	100	100	100	100	100	100	100	100	100
2003		111	148	103	104	108	108	102	107	117	118	101
2004		108	138	98	99	102	108	112	102	133	126	100
2005		108	141	99	100	102	109	116	124	159	154	118
2006		119P	137P	111	105	109	135	127	182	205	209	131
2007		121P	140P	113P	114P	122P	129P	121P	140P	158P	161P	128P
2008		122P	143P	115P	116P	125P	134P	125P	147P	166P	169P	133P
2009		124P	145P	117P	119P	128P	140P	130P	154P	173P	177P	139P
2010		126P	148P	120P	120P	130P	145P	135P	161P	181P	185P	144P

SELECTED RATIOS
For 2002	Avg. of All Manufact.	Analyzed Industry	Index	For 2002	Avg. of All Manufact.	Analyzed Industry	Index
Sources: Same as General Statistics. The ‘Average of All Manufacturing’ column represents the average of all manufacturing industries reported for the most recent complete year available. The Index shows the relationship between the Average and the Analyzed Industry. For example, 100 means that they are equal; 500 that the Analyzed Industry is five times the average; 50 means that the Analyzed Industry is half the national average. The abbreviation ‘na’ is used to show that data are ‘not available’. Ratios shown for 2002, the last complete census year.
Employees per Establishment	42	77	184	Value Added per Production Worker	182,367	496,460	272
Payroll per Establishment	1,639,184	4,141,216	253	Cost per Establishment	5,769,015	8,617,905	149
Payroll per Employee	39,053	53,528	137	Cost per Employee	137,446	111,393	81
Production Workers per Establishment	30	38	129	Cost per Production Worker	195,506	225,743	115
Wages per Establishment	694,845	1,617,324	233	Shipments per Establishment	11,158,348	26,319,932	236
Wages per Production Worker	23,548	42,365	180	Shipments per Employee	265,847	340,205	128
Hours per Production Worker	1,980	1,929	97	Shipments per Production Worker	378,144	689,442	182
Wages per Hour	11.89	21.96	185	Investment per Establishment	361,338	1,849,662	512
Value Added per Establishment	5,381,325	18,952,703	352	Investment per Employee	8,609	23,908	278
Value Added per Employee	128,210	244,978	191	Investment per Production Worker	12,245	48,451	396

LEADING COMPANIES Number shown: 75 Total sales ($ mil): 94,476 Total employment (000): 216.8
Company Name	Address				CEO Name	Phone	Co. Type	Sales ($ mil)	Empl. (000)
Source: Ward's Business Directory of U.S. Private and Public Companies, Volumes 1 and 2, 2008. The company type code used is as follows: P - Public, R - Private, S - Subsidiary, D - Division, J - Joint Venture, A - Affiliate, G - Group. Sales are in millions of dollars, employees are in thousands. An asterisk (*) indicates an estimated sales volume. The symbol < stands for ‘less than’. Company names and addresses are truncated, in some cases, to fit into the available space.
Merck and Company Inc.	PO Box 100	Whitehouse Sta	NJ	08889	David Anstice	908-423-1000	P	24,198	59.8
Amgen Inc.	1 Amgen Center Dr.	Thousand Oaks	CA	91320		805-447-1000	P	14,771	21.0
Baxter International Inc.	1 Baxter Pky.	Deerfield	IL	60015		847-948-2000	P	11,263	46.0
Genentech Inc.	1 DNA Way	S San Francisco	CA	94080		650-225-1000	P	9,443	10.5
Monsanto Co.	800 N Lindbergh	St. Louis	MO	63167		314-694-1000	P	8,563	18.8
Pasteur Merieux Connaught Labs	PO Box 187	Swiftwater	PA	18370	Michel Greco	570-839-7187	S	5,342*	9.0
Gilead Sciences Inc.	333 Lakeside Dr.	Foster City	CA	94404		650-574-3000	P	4,230	3.0
Genzyme Corp.	500 Kendall St.	Cambridge	MA	02142		617-252-7500	P	3,458	10.0
Biogen Idec Inc.	14 Cambridge Ctr.	Cambridge	MA	02142	James C. Mullen	617-679-2000	P	2,137	4.3
Arkema Inc.	2000 Market St.	Philadelphia	PA	19103	Thierry Le Henaff	215-419-7000	S	1,600*	2.6
Invitrogen Corp.	PO Box 6482	Carlsbad	CA	92008		760-603-7200	P	1,282	4.3
Charles River Labs Int’l	251 Ballardvale St.	Wilmington	MA	01887	James C. Foster	978-658-6000	P	1,231	8.5
Talecris Biotherapeutics Hold.	4101 Resrch Cmns	Research Tri Pk	NC	27709	Lawrence D. Stern	919-316-6300	R	1,115	3.5
Boehringer Ingelheim Vetmedica	2621 N Belt Hwy.	Saint Joseph	MO	64506	George Heidgerken	816-233-2571	S	897*	0.3
ImClone Systems Inc.	180 Varick St.	New York	NY	10014	Alexander Denner	212-645-1405	P	591	1.0
Integra LifeSciences Holdings	311 Enterprise Dr.	Plainsboro	NJ	08536		609-275-0500	P	419	1.8
PDL BioPharma Inc.	1400 Seaport Blvd.	Redwood City	CA	94063	L. Patrick Gage	650-454-1000	P	415	1.1
Twin Laboratories Inc.	150 Motor Pky.	Hauppauge	NY	11788	Ross Blechman	631-467-3140	R	398*	0.7
Martek Biosciences Corp.	6480 Dobbin Rd.	Columbia	MD	21045	Steve Dubin	410-740-0081	P	307	0.5
Enzon Pharmaceuticals Inc.	685 Rte. 202/206	Bridgewater	NJ	08807	Jeffrey H. Buchalter	908-541-8600	P	186	0.4
American Peptide Company Inc.	777 E Evelyn Ave.	Sunnyvale	CA	94086	Kenichi Ito	408-733-7604	R	134*	<0.1
MedImmune Vaccines Inc.	319 N Bernardo	Mountain View	CA	94043	David M. Mott	650-603-2000	S	127*	0.5
Meridian Bioscience Inc.	3471 River Hills Dr	Cincinnati	OH	45244		513-271-3700	P	123	0.4
Osteotech Inc.	51 James Way	Eatontown	NJ	07724		732-542-2800	P	104	0.3
Intervet Inc.	PO Box 318	Millsboro	DE	19966	Klaus Olbers	302-934-8051	S	103*	0.5
Stratagene Cloning Systems	11011 N Torrey Pine	La Jolla	CA	92037	Joseph A. Sorge	858-373-6300	P	96	0.5
Rigel Pharmaceuticals Inc.	1180 Veterans Blvd.	S San Francisco	CA	94080	James M. Gower	650-624-1100	P	92	0.2
Nabi Biopharmaceuticals	12276 Wilkins Ave.	Rockville	MD	20852		301-770-3099	P	90	0.7
NPS Pharmaceuticals Inc.	383 Colorow Dr.	Salt Lake City	UT	84108	N. Anthony Coles	801-583-4939	P	86	<0.1
Research & Diagnostic Systems	614 McKinley NE	Minneapolis	MN	55413	Thomas E. Oland	612-379-2956	S	86*	0.6
CV Therapeutics Inc.	3172 Porter Dr.	Palo Alto	CA	94304		650-384-8500	P	83	0.5
Heska Corp.	3760 Rocky Mtn	Loveland	CO	80538		970-493-7272	P	82	0.3
Clontech Laboratories Inc.	1290 Terra Bella Av	Mountain View	CA	94043	Deborah J. Neff	650-919-7300	S	71*	0.3
LifeCore Biomedical Inc.	3515 Lyman Blvd.	Chaska	MN	55318	Dennis J. Allingham	952-368-4300	P	70	0.2
Irvine Scientific Sales Co.	2511 Daimler St.	Santa Ana	CA	92705	Michael Kelly	949-261-7800	R	65*	<0.1
Antigenics Inc.	3 Forbes Rd.	Lexington	MA	02421	Garo H. Armen	781-674-4400	S	64*	0.3
Diamond Animal Health Inc.	2538 SE 43rd St.	Des Moines	IA	50327		515-263-8600	S	58*	0.1
Embrex Inc.	PO Box 13989	Research Tri Pk	NC	27709		919-941-5185	S	53	0.3
Hardy Media Inc.	1430 W McCoy Ln.	Santa Maria	CA	93455	Jay Hardy	805-346-2766	R	51*	0.1
Alnylam Pharmaceuticals Inc.	300 3rd St., 3rd Fl	Cambridge	MA	02142		617-551-8200	P	51	0.1
Trimeris Inc.	3500 Paramount	Morrisville	NC	27560	Richard Crout	919-419-6050	P	49	<0.1
BioForm Medical Inc.	1875 S Grant St.	San Mateo	CA	94402	Steven L. Basta	650-286-4000	P	47	0.3
Fujirebio Diagnostics Inc.	201 Great Vly Pky.	Malvern	PA	19355	Takeo Hayashi	610-240-3800	S	46*	0.1
Affymax Inc.	4001 Miranda Ave.	Palo Alto	CA	94304	Arlene M. Morris	650-812-8700	P	44	0.2
Nutrition 21 Inc.	4 Manhattanville Rd	Purchase	NY	10577	John H. Gutfreund	914-701-4500	P	42	<0.1
ZymoGenetics Inc.	1201 Eastlake Ave.	Seattle	WA	98102	Bruce L.A. Carter	206-442-6600	P	39	0.6
Covance Research Products Inc.	PO Box 7200	Denver	PA	17517		717-336-4921	S	38*	0.2
Sigma-Genosys	1442 Lk Front Cir.	The Woodlands	TX	77380		281-363-3693	S	36*	0.2
Encysive Pharmaceuticals Inc.	4848 Loop Central	Houston	TX	77081	Ron Anderson	713-796-8822	P	36	0.1
Research Seeds Inc.	PO Box 339	Nampa	ID	83653	Mark McCaslin	208-466-3568	R	33*	<0.1
Biomune Co.	8901 Rosehill Rd.	Shawnee Msn	KS	66215		913-894-0230	R	33*	<0.1
Anika Therapeutics Inc.	32 Wiggins Ave.	Bedford	MA	01730		781-457-9000	P	31	<0.1
Worthington Bio Chemical Corp.	730 Vassar Ave.	Lakewood	NJ	08701	Von Worthington	732-942-1660	R	29*	<0.1
Santa Cruz Biotechnology Inc.	2145 Delaware Ave.	Santa Cruz	CA	95060	John Stephenson	831-457-3800	R	28*	0.1
PML Microbiologicals Inc.	27120 SW 95th Ave.	Wilsonville	OR	97070	Charlie Mamrak	503-570-2500	S	28*	0.1
Targacept Inc.	200 E First St.	Winston-Salem	NC	27101		336-480-2100	P	28	<0.1
Intarcia Therapeutics Inc.	2000 Powell St.	Emeryville	CA	94608	K. Alice Leung	510-652-2600	R	27*	<0.1
Accentia BioPharmaceuticals	324 S Hyde Park	Tampa	FL	33606	Steven R. Arikian	813-864-2554	P	25	0.3
Microban Products Co.	11515 Vanstory Dr.	Huntersville	NC	28078	William Rubinstein	704-875-0806	R	25*	<0.1
International Immunology Corp.	25549 Adams Ave.	Murrieta	CA	92562	Shunsaku Shibota	951-677-5629	R	25*	<0.1
Seattle Genetics Inc.	21823 30th Dr. SE	Bothell	WA	98021		425-527-4000	P	22	0.2
Momenta Pharmaceuticals Inc.	675 West Kendall St	Cambridge	MA	02142		617-491-9700	P	22	0.2
Trubion Pharmaceuticals Inc.	2401 4th Ave., 1050	Seattle	WA	98121	Peter A. Thompson	206-838-0500	P	20	<0.1
ImmunoVision Inc.	1820 Ford Ave.	Springdale	AR	72764	Giorgio D’Urso		S	20*	<0.1
MML Diagnostics Packaging Inc.	PO Box 458	Troutdale	OR	97060	Dale Pestes	503-666-8398	R	19*	<0.1
Bachem Inc.	3132 Kashiwa St.	Torrance	CA	90505	Phillip Ottiger	310-539-4171	R	18*	<0.1
Neurobiological Technologies	2000 Powell St.	Emeryville	CA	94608	Abraham E. Cohen	510-595-6000	P	18	<0.1
Curis Inc.	45 Moulton St.	Cambridge	MA	02138	James McNab	617-503-6500	P	16	<0.1
North American Scientific Inc.	20200 Sunburst St.	Chatsworth	CA	91311	Irwin Gruverman	818-734-8600	P	15	<0.1
Vical Inc.	10390 Pac. Cntr Ct	San Diego	CA	92121		858-646-1100	P	15	0.1
Antibodies Inc.	PO Box 1560	Davis	CA	95617	Richard Krogsrud	530-758-4400	R	15*	<0.1
Palatin Technologies Inc.	4-C Cedar Brook Dr.	Cranbury	NJ	08512	John K.A. Prendergast	609-495-2200	P	14	<0.1
Repligen Corp.	41 Seyon St. Bldg 1	Waltham	MA	02453	Walter C. Herlihy	781-250-0111	P	14	<0.1
GTC Biotherapeutics Inc.	175 Crossing Blvd.	Framingham	MA	01702	Geoffrey F. Cox	508-620-9700	P	14	0.2
Cypress Bioscience Inc.	4350 Executive Dr.	San Diego	CA	92121		858-452-2323	P	14	<0.1

MATERIALS CONSUMED
Material	Quantity	Delivered Cost ($ million)
Source: 2002 Economic Census. Explanation of symbols used: (D): Withheld to avoid disclosure of competitive data; na: Not available; (S): Withheld because statistical norms were not met; (X): Not applicable; (Z): Less than half the unit shown; nec: Not elsewhere classified; nsk: Not specified by kind; - : zero; p : 10–19 percent estimated; q : 20–29 percent estimated.
Antibiotics (bulk), for human and veterinary use	(X)	29.1
Antibiotics (bulk), for animal feeds	(X)	(D)
Vitamins, natural and synthetic, human and veterinary use (bulk)	(X)	(D)
Vitamins, natural and synthetic, for animal feeds (bulk)	(X)	(D)
Agricultural products, crude (incl. flowers, grains, seeds, herbs, etc.)	(X)	14.7
Processed food and kindred products (lactose, meat packing plant products, yeast, etc.)	(X)	6.0
Blood derivatives and extenders	(X)	875.9
All other bulk medicinal and botanical uncompounded drugs	(X)	82.5
Gelatin (pharmaceutical grade) and gelatin capsules	(X)	(D)
Alcohols, excluding ethyl (100 percent basis)	(X)	2.4
Cyclic crudes and intermediates (including organic colors)	(X)	(D)
Other synthetic organic chemicals	(X)	41.1
Fabricated plastics products (excluding containers)	(X)	19.3
Metal closures and crowns for containers	(X)	3.0
Labels, coupons, instructions, and other printed material	(X)	15.1
Plastics containers	(X)	26.0
Glass containers	(X)	21.9
Metal containers	(X)	(D)
Paperboard containers, boxes, and corrugated paperboard	(X)	12.0
All other materials, components, parts, containers, and supplies	(X)	420.3
Materials, ingredients, containers, and supplies, nsk	(X)	252.6

PRODUCT SHARE DETAILS
Product or Product Class Shipments	Mil. $	Product or Product Class Shipments	Mil. $
Source: 2002 Economic Census. The values are product shipments in millions of dollars for 2002. Total product shipments may be lower or higher than industry shipments. See Introduction for a full discussion. Values of indented subcategories are summed in the main heading(s). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. The abbreviation nsk stands for ‘not specified by kind’ and nec for ‘not elsewhere classified’. A dash (-) means zero.
BIOLOGICAL PRODUCTS, EXCEPT DIAGNOSTICS	8,540.2	industrial, and other uses, nec	1,731.4
Blood and blood derivatives, for human use	1,388.1	Biological veterinary vaccines, bacterins, toxoids, other antigens, and other biological products	917.5
Biological products, blood and blood derivatives, for human use	1,387.7	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, veterinary vaccines, including vaccines against foot-and-mouth disease	585.6
Biological products, diagnostic, blood and blood derivatives, human blood plasma, for human use	953.7	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, bacterins, toxoids, and other antigens, except allergens, for active immunization	65.0
Biological products, except diagnostic, blood and blood derivatives, other blood and blood derivatives or fractions, except those used for passive immunization	434.0	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, other biological products, including veterinary blood derivatives, antitoxins, immune serums, and allergens, except diagnostics	266.9
Blood and blood derivatives, for human use, nsk	0.3	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, biological products for industrial and other uses, except culture media	679.2
Vaccines, toxoids, and antigens, except allergens, for human use	3,015.3	Biological products for industrial and all other miscellaneous uses, non-diagnostic culture media	95.1
Other biologics, except diagnostic, for human use	2,165.2	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, nsk	39.7
Biological products, except diagnostic, for human use	2,165.2	Biological products, except diagnostics, nsk, total	240.2
Biological products, except diagnostic, other biologics, antitoxins, antivenoms, immune globulins, therapeutic immune serums, etc., for therapeutic use and passive immunization	2,052.4
Biological products, except diagnostic, other biologics, allergenic extracts and other biologics for human use, including poison ivy and oak extracts, except diagnostic allergens	112.8
Biological products, except diagnostic, for veterinary ,

INPUTS AND OUTPUTS FOR BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Compensation of employees	20.9		Pharmaceutical preparations	23.6	Manufg.
Management of companies & enterprises	15.3	Services	Exports of goods & services	12.8	Cap Inv
Biological products (except diagnostic)	13.2	Manufg.	Medicinal & botanical manufacturing	12.0	Manufg.
Wholesale trade	8.6	Trade	Biological products (except diagnostic)	11.2	Manufg.
Scientific research & development services	5.4	Services	Physician, dentist, other health practitioner offices	9.5	Services
Pharmaceutical preparations	2.9	Manufg.	Medical & diagnostic labs & outpatient services	6.2	Services
Medicinal & botanical manufacturing	1.3	Manufg.	In-vitro diagnostic substances	4.7	Manufg.
Management, scientific, & technical consulting	1.2	Services	Change in private inventories	4.6	In House
Advertising & related services	1.2	Services	Cattle	2.0	Agric.
Noncomparable imports	1.1	Foreign	General Federal government services, nondefense	1.9	Fed Govt
Power generation & supply	0.7	Util.	Agriculture & forestry services	1.8	Agric.
Real estate	0.6	Fin/R.E.	Veterinary services	1.5	Services

INPUTS AND OUTPUTS FOR BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING - Continued
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Source: Benchmark Input-Output Accounts for the U.S. Economy, 2002, U.S. Department of Commerce, Washington, D.C., January 2008. The abbreviation nec stands for ‘not elsewhere classified’.
Basic organic chemicals, nec	0.5	Manufg.	Poultry & eggs	1.3	Agric.
Truck transportation	0.4	Util.	Nursing & residential care facilities	0.9	Services
Plastics products, nec	0.4	Manufg.	Amusement parks, arcades, & gambling	0.9	Services
Taxes on production & imports, less subsidies	0.3		Retail trade	0.8	Trade
Lessors of nonfinancial assets	0.3	Fin/R.E.	General S/L govt. services	0.7	S/L Govt
Maintenance/repair of nonresidential structures	0.3	Construct.	Individual & family services	0.7	Services
Services to buildings & dwellings	0.2	Services	Architectural, engineering, & related services	0.5	Services
Business support services	0.2	Services	Community food, housing, relief, & rehabilitation	0.5	Services
Telecommunications	0.2	Services	Museums, historical sites, zoos, & parks	0.5	Services
Warehousing & storage	0.2	Util.	Scientific research & development services	0.4	Services
In-vitro diagnostic substances	0.2	Manufg.	Maintenance/repair of nonresidential structures	0.3	Construct.
Legal services	0.2	Services	Other S/L govt. enterprises	0.2	S/L Govt
Automotive equipment rental & leasing	0.2	Fin/R.E.	Wood containers & pallets	0.1	Manufg.
Employment services	0.2	Services	Hospitals	0.1	Services
Printing	0.2	Manufg.	Personal services, nec	0.1	Services
Automotive repair & maintenance, ex. car washes	0.2	Services
Animal, except poultry, processing	0.2	Manufg.
Chemical products & preparations, nec	0.2	Manufg.
Glass containers	0.2	Manufg.
Commercial & industrial equipment repair/maintenance	0.2	Services
Environmental & other technical consulting services	0.1	Services
Petroleum refineries	0.1	Manufg.
Paperboard containers	0.1	Manufg.
Office administrative services	0.1	Services
Natural gas distribution	0.1	Util.
Data processing, hosting, & related services	0.1	Services
Waste management & remediation services	0.1	Services
Specialized design services	0.1	Services

OCCUPATIONS EMPLOYED BY PHARMACEUTICAL & MEDICINE MANUFACTURING
Occupation	% of Total 2006	Change to 2016	Occupation	% of Total 2006	Change to 2016
Source: Industry-Occupation Matrix, Bureau of Labor Statistics, December 4, 2007. These data are reported based on 4-digit NAICS categories but have been matched to corresponding 6-digit NAICS industry codes. The change reported for each occupation to the year 2016 is a percent of growth or decline as estimated by the Bureau of Labor Statistics. The abbreviation nec stands for ‘not elsewhere classified’.
Packaging & filling machine operators & tenders	7.0	13.4	General & operations managers	1.6	13.4
Chemists	5.2	13.4	Biochemists & biophysicists	1.4	26.0
Mixing & blending machine operators & tenders	3.6	26.0	Machine feeders & offbearers	1.4	13.4
Chemical equipment operators & tenders	3.5	26.0	Packers & packagers, hand	1.4	0.8
Medical scientists, exc epidemiologists	3.4	26.0	Shipping, receiving, & traffic clerks	1.4	21.3
Inspectors, testers, sorters, samplers, & weighers	3.0	18.8	Customer service representatives	1.4	38.6
First-line supervisors/managers of production workers	2.6	26.0	Secretaries, exc legal, medical, & executive	1.3	12.1
Biological technicians	2.5	26.0	Industrial production managers	1.3	26.0
Chemical technicians	2.3	26.0	Managers, nec	1.3	26.0
Maintenance & repair workers, general	2.1	26.0	Production workers, nec	1.2	23.7
Sales representatives, wholesale & manufacturing, tech	2.0	26.0	Office clerks, general	1.2	24.2
Separating, precipitating, & still machine operators	1.9	26.0	Microbiologists	1.1	26.0
Business operation specialists, nec	1.8	38.6	Industrial machinery mechanics	1.1	44.9
Executive secretaries & administrative assistants	1.7	26.0	Accountants & auditors	1.1	26.0
Team assemblers	1.7	26.0	Natural sciences managers	1.1	26.0
Laborers & freight, stock, & material movers, hand	1.6	13.4	Production, planning, & expediting clerks	1.1	26.0

INDUSTRY DATA BY STATE
State	Establishments	Shipments				Employment			Cost as % of Shipments	Investment per Employee ($)
State	Establishments	Total ($ mil)	% of U.S.	Per Establ.	Total Number	% of U.S.	Per Establ.	Wages ($/hour)	Cost as % of Shipments	Investment per Employee ($)
Source: 2002 Economic Census. The states are in descending order of shipments or establishments (if shipment data are missing for the majority). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. States marked with (D) are sorted by number of establishments. A dash (-) indicates that the data element cannot be calculated. Data may not show all states active in the NAICS category. All data available at the time of publication are shown.
North Carolina	12	1,356.0	17.4	113,001.1	2,983	13.1	249	20.49	37.9	43,215
California	45	1,109.9	14.2	24,664.7	4,281	18.7	95	27.49	44.2	21,788
Maryland	13	835.3	10.7	64,253.3	1,029	4.5	79	21.76	7.8	13,920
Massachusetts	15	803.6	10.3	53,572.6	1,334	5.8	89	23.13	9.4	27,343
Iowa	11	444.0	5.7	40,364.3	1,713	7.5	156	12.88	33.4	12,640
Wisconsin	10	198.0	2.5	19,803.1	932	4.1	93	23.36	28.0	10,558
New York	6	132.6	1.7	22,103.0	434	1.9	72	23.19	42.4	8,763
Georgia	8	124.9	1.6	15,614.9	434	1.9	54	15.97	26.9	25,477
Texas	24	88.6	1.1	3,693.0	512	2.2	21	19.15	22.9	10,219
Missouri	10	81.5	1.0	8,149.7	529	2.3	53	18.44	25.9	14,439
Nebraska	7	80.7	1.0	11,532.6	448	2.0	64	18.84	36.0	28,857
Kansas	7	54.9	0.7	7,836.0	257	1.1	37	15.71	31.0	10,354
Minnesota	9	30.7	0.4	3,415.2	172	0.8	19	19.36	31.2	11,390
Maine	7	27.6	0.4	3,940.0	120	0.5	17	13.12	41.6	46,700
Florida	7	20.5	0.3	2,922.7	113	0.5	16	15.46	24.9	3,894

NAICS 325414 - Biological Product (Except Diagnostic) Manufacturing

views updated

NAICS 325414 - Biological Product (Except Diagnostic) Manufacturing

GENERAL STATISTICS
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: 1992, 1997, 2002 Economic Census; other years, up to 2006, are from the Annual Survey of Manufactures. Establishment counts for non-Census years are from County Business Patterns; 1997 and 2002 values are from the 1997 and 2002 censuses respectively, reported in the Federal Government's NAICS format. Other years were originally reported in equivalent SIC format. ‘P’s show projections by the editors.
1991		248	127	12.1	6.4	12.1	391.5	11.00	962.4	1,483.3	2,405.6	108.3
1992	193	275	140	18.4	8.0	15.1	627.2	12.48	1,313.5	2,754.6	3,974.0	294.3
1993		296	137	19.0	9.2	18.1	732.5	12.57	1,483.2	3,479.3	4,914.0	405.1
1994		286	142	19.8	9.9	18.6	788.3	13.81	1,570.3	3,829.9	5,310.2	360.6
1995		284	117	21.1	11.0	20.4	854.5	13.74	1,719.2	4,564.3	6,226.6	452.7
1996		277	107	19.6	9.7	19.1	865.5	14.06	1,713.2	4,661.5	6,402.0	359.5
1997	268	364	172	23.3	12.1	25.0	1,020.1	15.72	2,134.0	3,728.9	5,685.9	426.9
1998		347	158	24.1	12.2	24.6	1,096.6	16.90	2,257.6	3,898.3	6,056.8	390.0
1999		358	155	21.2	11.4	22.8	958.0	18.15	2,272.6	3,711.7	5,798.6	371.8
2000		356	153	22.8	11.8	26.5	1,114.1	15.74	2,726.5	4,257.3	6,827.5	570.7
2001		358	144	24.0	11.9	27.1	1,207.1	16.35	2,866.3	4,810.4	7,521.5	620.0
2002	229	296	130	22.9	11.3	21.8	1,225.8	21.96	2,550.9	5,610.0	7,790.7	547.5
2003		330	193	23.5	11.7	23.5	1,319.5	22.47	2,733.8	6,549.4	9,176.3	553.9
2004		320	179	22.4	11.2	22.3	1,327.3	24.64	2,593.5	7,439.2	9,847.8	548.2
2005		319	183	22.7	11.3	22.3	1,341.1	25.48	3,154.0	8,936.7	11,983.2	645.0
2006		353P	178P	25.4	11.9	23.8	1,657.0	27.89	4,645.7	11,506.2	16,275.2	714.5
2007		358P	182P	25.8P	12.9P	26.6P	1,583.3P	26.48P	3,574.9P	8,854.2P	12,524.0P	702.4P
2008		363P	185P	26.4P	13.1P	27.2P	1,648.1P	27.51P	3,751.6P	9,291.9P	13,143.1P	730.8P
2009		367P	189P	26.9P	13.4P	27.8P	1,712.9P	28.55P	3,928.3P	9,729.5P	13,762.1P	759.3P
2010		372P	193P	27.4P	13.6P	28.4P	1,777.6P	29.58P	4,105.0P	10,167.1P	14,381.1P	787.7P

INDICES OF CHANGE
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: Same as General Statistics. Values reflect change from the base year, 2002. Values above 100 mean greater than 2002, values below 100 mean less than 2002, and the values of 100 in other years means same as 2002. ‘P’s show projections by the editors.
1992	84	93	108	80	71	69	51	57	51	49	51	54
1997	117	123	132	102	107	115	83	72	84	66	73	78
2001		121	111	105	105	124	98	74	112	86	97	113
2002	100	100	100	100	100	100	100	100	100	100	100	100
2003		111	148	103	104	108	108	102	107	117	118	101
2004		108	138	98	99	102	108	112	102	133	126	100
2005		108	141	99	100	102	109	116	124	159	154	118
2006		119P	137P	111	105	109	135	127	182	205	209	131
2007		121P	140P	113P	114P	122P	129P	121P	140P	158P	161P	128P
2008		122P	143P	115P	116P	125P	134P	125P	147P	166P	169P	133P
2009		124P	145P	117P	119P	128P	140P	130P	154P	173P	177P	139P
2010		126P	148P	120P	120P	130P	145P	135P	161P	181P	185P	144P

SELECTED RATIOS
For 2002	Avg. of All Manufact.	Analyzed Industry	Index	For 2002	Avg. of All Manufact.	Analyzed Industry	Index
Sources: Same as General Statistics. The ‘Average of All Manufacturing’ column represents the average of all manufacturing industries reported for the most recent complete year available. The Index shows the relationship between the Average and the Analyzed Industry. For example, 100 means that they are equal; 500 that the Analyzed Industry is five times the average; 50 means that the Analyzed Industry is half the national average. The abbreviation ‘na’ is used to show that data are ‘not available’. Ratios shown for 2002, the last complete census year.
Employees per Establishment	42	77	184	Value Added per Production Worker	182,367	496,460	272
Payroll per Establishment	1,639,184	4,141,216	253	Cost per Establishment	5,769,015	8,617,905	149
Payroll per Employee	39,053	53,528	137	Cost per Employee	137,446	111,393	81
Production Workers per Establishment	30	38	129	Cost per Production Worker	195,506	225,743	115
Wages per Establishment	694,845	1,617,324	233	Shipments per Establishment	11,158,348	26,319,932	236
Wages per Production Worker	23,548	42,365	180	Shipments per Employee	265,847	340,205	128
Hours per Production Worker	1,980	1,929	97	Shipments per Production Worker	378,144	689,442	182
Wages per Hour	11.89	21.96	185	Investment per Establishment	361,338	1,849,662	512
Value Added per Establishment	5,381,325	18,952,703	352	Investment per Employee	8,609	23,908	278
Value Added per Employee	128,210	244,978	191	Investment per Production Worker	12,245	48,451	396

LEADING COMPANIES Number shown: 75 Total sales ($ mil): 94,476 Total employment (000): 216.8
Company Name	Address				CEO Name	Phone	Co. Type	Sales ($ mil)	Empl. (000)
Source: Ward's Business Directory of U.S. Private and Public Companies, Volumes 1 and 2, 2008. The company type code used is as follows: P - Public, R - Private, S - Subsidiary, D - Division, J - Joint Venture, A - Affiliate, G - Group. Sales are in millions of dollars, employees are in thousands. An asterisk (*) indicates an estimated sales volume. The symbol < stands for ‘less than’. Company names and addresses are truncated, in some cases, to fit into the available space.
Merck and Company Inc.	PO Box 100	Whitehouse Sta	NJ	08889	David Anstice	908-423-1000	P	24,198	59.8
Amgen Inc.	1 Amgen Center Dr.	Thousand Oaks	CA	91320		805-447-1000	P	14,771	21.0
Baxter International Inc.	1 Baxter Pky.	Deerfield	IL	60015		847-948-2000	P	11,263	46.0
Genentech Inc.	1 DNA Way	S San Francisco	CA	94080		650-225-1000	P	9,443	10.5
Monsanto Co.	800 N Lindbergh	St. Louis	MO	63167		314-694-1000	P	8,563	18.8
Pasteur Merieux Connaught Labs	PO Box 187	Swiftwater	PA	18370	Michel Greco	570-839-7187	S	5,342*	9.0
Gilead Sciences Inc.	333 Lakeside Dr.	Foster City	CA	94404		650-574-3000	P	4,230	3.0
Genzyme Corp.	500 Kendall St.	Cambridge	MA	02142		617-252-7500	P	3,458	10.0
Biogen Idec Inc.	14 Cambridge Ctr.	Cambridge	MA	02142	James C. Mullen	617-679-2000	P	2,137	4.3
Arkema Inc.	2000 Market St.	Philadelphia	PA	19103	Thierry Le Henaff	215-419-7000	S	1,600*	2.6
Invitrogen Corp.	PO Box 6482	Carlsbad	CA	92008		760-603-7200	P	1,282	4.3
Charles River Labs Int’l	251 Ballardvale St.	Wilmington	MA	01887	James C. Foster	978-658-6000	P	1,231	8.5
Talecris Biotherapeutics Hold.	4101 Resrch Cmns	Research Tri Pk	NC	27709	Lawrence D. Stern	919-316-6300	R	1,115	3.5
Boehringer Ingelheim Vetmedica	2621 N Belt Hwy.	Saint Joseph	MO	64506	George Heidgerken	816-233-2571	S	897*	0.3
ImClone Systems Inc.	180 Varick St.	New York	NY	10014	Alexander Denner	212-645-1405	P	591	1.0
Integra LifeSciences Holdings	311 Enterprise Dr.	Plainsboro	NJ	08536		609-275-0500	P	419	1.8
PDL BioPharma Inc.	1400 Seaport Blvd.	Redwood City	CA	94063	L. Patrick Gage	650-454-1000	P	415	1.1
Twin Laboratories Inc.	150 Motor Pky.	Hauppauge	NY	11788	Ross Blechman	631-467-3140	R	398*	0.7
Martek Biosciences Corp.	6480 Dobbin Rd.	Columbia	MD	21045	Steve Dubin	410-740-0081	P	307	0.5
Enzon Pharmaceuticals Inc.	685 Rte. 202/206	Bridgewater	NJ	08807	Jeffrey H. Buchalter	908-541-8600	P	186	0.4
American Peptide Company Inc.	777 E Evelyn Ave.	Sunnyvale	CA	94086	Kenichi Ito	408-733-7604	R	134*	<0.1
MedImmune Vaccines Inc.	319 N Bernardo	Mountain View	CA	94043	David M. Mott	650-603-2000	S	127*	0.5
Meridian Bioscience Inc.	3471 River Hills Dr	Cincinnati	OH	45244		513-271-3700	P	123	0.4
Osteotech Inc.	51 James Way	Eatontown	NJ	07724		732-542-2800	P	104	0.3
Intervet Inc.	PO Box 318	Millsboro	DE	19966	Klaus Olbers	302-934-8051	S	103*	0.5
Stratagene Cloning Systems	11011 N Torrey Pine	La Jolla	CA	92037	Joseph A. Sorge	858-373-6300	P	96	0.5
Rigel Pharmaceuticals Inc.	1180 Veterans Blvd.	S San Francisco	CA	94080	James M. Gower	650-624-1100	P	92	0.2
Nabi Biopharmaceuticals	12276 Wilkins Ave.	Rockville	MD	20852		301-770-3099	P	90	0.7
NPS Pharmaceuticals Inc.	383 Colorow Dr.	Salt Lake City	UT	84108	N. Anthony Coles	801-583-4939	P	86	<0.1
Research & Diagnostic Systems	614 McKinley NE	Minneapolis	MN	55413	Thomas E. Oland	612-379-2956	S	86*	0.6
CV Therapeutics Inc.	3172 Porter Dr.	Palo Alto	CA	94304		650-384-8500	P	83	0.5
Heska Corp.	3760 Rocky Mtn	Loveland	CO	80538		970-493-7272	P	82	0.3
Clontech Laboratories Inc.	1290 Terra Bella Av	Mountain View	CA	94043	Deborah J. Neff	650-919-7300	S	71*	0.3
LifeCore Biomedical Inc.	3515 Lyman Blvd.	Chaska	MN	55318	Dennis J. Allingham	952-368-4300	P	70	0.2
Irvine Scientific Sales Co.	2511 Daimler St.	Santa Ana	CA	92705	Michael Kelly	949-261-7800	R	65*	<0.1
Antigenics Inc.	3 Forbes Rd.	Lexington	MA	02421	Garo H. Armen	781-674-4400	S	64*	0.3
Diamond Animal Health Inc.	2538 SE 43rd St.	Des Moines	IA	50327		515-263-8600	S	58*	0.1
Embrex Inc.	PO Box 13989	Research Tri Pk	NC	27709		919-941-5185	S	53	0.3
Hardy Media Inc.	1430 W McCoy Ln.	Santa Maria	CA	93455	Jay Hardy	805-346-2766	R	51*	0.1
Alnylam Pharmaceuticals Inc.	300 3rd St., 3rd Fl	Cambridge	MA	02142		617-551-8200	P	51	0.1
Trimeris Inc.	3500 Paramount	Morrisville	NC	27560	Richard Crout	919-419-6050	P	49	<0.1
BioForm Medical Inc.	1875 S Grant St.	San Mateo	CA	94402	Steven L. Basta	650-286-4000	P	47	0.3
Fujirebio Diagnostics Inc.	201 Great Vly Pky.	Malvern	PA	19355	Takeo Hayashi	610-240-3800	S	46*	0.1
Affymax Inc.	4001 Miranda Ave.	Palo Alto	CA	94304	Arlene M. Morris	650-812-8700	P	44	0.2
Nutrition 21 Inc.	4 Manhattanville Rd	Purchase	NY	10577	John H. Gutfreund	914-701-4500	P	42	<0.1
ZymoGenetics Inc.	1201 Eastlake Ave.	Seattle	WA	98102	Bruce L.A. Carter	206-442-6600	P	39	0.6
Covance Research Products Inc.	PO Box 7200	Denver	PA	17517		717-336-4921	S	38*	0.2
Sigma-Genosys	1442 Lk Front Cir.	The Woodlands	TX	77380		281-363-3693	S	36*	0.2
Encysive Pharmaceuticals Inc.	4848 Loop Central	Houston	TX	77081	Ron Anderson	713-796-8822	P	36	0.1
Research Seeds Inc.	PO Box 339	Nampa	ID	83653	Mark McCaslin	208-466-3568	R	33*	<0.1
Biomune Co.	8901 Rosehill Rd.	Shawnee Msn	KS	66215		913-894-0230	R	33*	<0.1
Anika Therapeutics Inc.	32 Wiggins Ave.	Bedford	MA	01730		781-457-9000	P	31	<0.1
Worthington Bio Chemical Corp.	730 Vassar Ave.	Lakewood	NJ	08701	Von Worthington	732-942-1660	R	29*	<0.1
Santa Cruz Biotechnology Inc.	2145 Delaware Ave.	Santa Cruz	CA	95060	John Stephenson	831-457-3800	R	28*	0.1
PML Microbiologicals Inc.	27120 SW 95th Ave.	Wilsonville	OR	97070	Charlie Mamrak	503-570-2500	S	28*	0.1
Targacept Inc.	200 E First St.	Winston-Salem	NC	27101		336-480-2100	P	28	<0.1
Intarcia Therapeutics Inc.	2000 Powell St.	Emeryville	CA	94608	K. Alice Leung	510-652-2600	R	27*	<0.1
Accentia BioPharmaceuticals	324 S Hyde Park	Tampa	FL	33606	Steven R. Arikian	813-864-2554	P	25	0.3
Microban Products Co.	11515 Vanstory Dr.	Huntersville	NC	28078	William Rubinstein	704-875-0806	R	25*	<0.1
International Immunology Corp.	25549 Adams Ave.	Murrieta	CA	92562	Shunsaku Shibota	951-677-5629	R	25*	<0.1
Seattle Genetics Inc.	21823 30th Dr. SE	Bothell	WA	98021		425-527-4000	P	22	0.2
Momenta Pharmaceuticals Inc.	675 West Kendall St	Cambridge	MA	02142		617-491-9700	P	22	0.2
Trubion Pharmaceuticals Inc.	2401 4th Ave., 1050	Seattle	WA	98121	Peter A. Thompson	206-838-0500	P	20	<0.1
ImmunoVision Inc.	1820 Ford Ave.	Springdale	AR	72764	Giorgio D’Urso		S	20*	<0.1
MML Diagnostics Packaging Inc.	PO Box 458	Troutdale	OR	97060	Dale Pestes	503-666-8398	R	19*	<0.1
Bachem Inc.	3132 Kashiwa St.	Torrance	CA	90505	Phillip Ottiger	310-539-4171	R	18*	<0.1
Neurobiological Technologies	2000 Powell St.	Emeryville	CA	94608	Abraham E. Cohen	510-595-6000	P	18	<0.1
Curis Inc.	45 Moulton St.	Cambridge	MA	02138	James McNab	617-503-6500	P	16	<0.1
North American Scientific Inc.	20200 Sunburst St.	Chatsworth	CA	91311	Irwin Gruverman	818-734-8600	P	15	<0.1
Vical Inc.	10390 Pac. Cntr Ct	San Diego	CA	92121		858-646-1100	P	15	0.1
Antibodies Inc.	PO Box 1560	Davis	CA	95617	Richard Krogsrud	530-758-4400	R	15*	<0.1
Palatin Technologies Inc.	4-C Cedar Brook Dr.	Cranbury	NJ	08512	John K.A. Prendergast	609-495-2200	P	14	<0.1
Repligen Corp.	41 Seyon St. Bldg 1	Waltham	MA	02453	Walter C. Herlihy	781-250-0111	P	14	<0.1
GTC Biotherapeutics Inc.	175 Crossing Blvd.	Framingham	MA	01702	Geoffrey F. Cox	508-620-9700	P	14	0.2
Cypress Bioscience Inc.	4350 Executive Dr.	San Diego	CA	92121		858-452-2323	P	14	<0.1

MATERIALS CONSUMED
Material	Quantity	Delivered Cost ($ million)
Source: 2002 Economic Census. Explanation of symbols used: (D): Withheld to avoid disclosure of competitive data; na: Not available; (S): Withheld because statistical norms were not met; (X): Not applicable; (Z): Less than half the unit shown; nec: Not elsewhere classified; nsk: Not specified by kind; - : zero; p : 10–19 percent estimated; q : 20–29 percent estimated.
Antibiotics (bulk), for human and veterinary use	(X)	29.1
Antibiotics (bulk), for animal feeds	(X)	(D)
Vitamins, natural and synthetic, human and veterinary use (bulk)	(X)	(D)
Vitamins, natural and synthetic, for animal feeds (bulk)	(X)	(D)
Agricultural products, crude (incl. flowers, grains, seeds, herbs, etc.)	(X)	14.7
Processed food and kindred products (lactose, meat packing plant products, yeast, etc.)	(X)	6.0
Blood derivatives and extenders	(X)	875.9
All other bulk medicinal and botanical uncompounded drugs	(X)	82.5
Gelatin (pharmaceutical grade) and gelatin capsules	(X)	(D)
Alcohols, excluding ethyl (100 percent basis)	(X)	2.4
Cyclic crudes and intermediates (including organic colors)	(X)	(D)
Other synthetic organic chemicals	(X)	41.1
Fabricated plastics products (excluding containers)	(X)	19.3
Metal closures and crowns for containers	(X)	3.0
Labels, coupons, instructions, and other printed material	(X)	15.1
Plastics containers	(X)	26.0
Glass containers	(X)	21.9
Metal containers	(X)	(D)
Paperboard containers, boxes, and corrugated paperboard	(X)	12.0
All other materials, components, parts, containers, and supplies	(X)	420.3
Materials, ingredients, containers, and supplies, nsk	(X)	252.6

PRODUCT SHARE DETAILS
Product or Product Class Shipments	Mil. $	Product or Product Class Shipments	Mil. $
Source: 2002 Economic Census. The values are product shipments in millions of dollars for 2002. Total product shipments may be lower or higher than industry shipments. See Introduction for a full discussion. Values of indented subcategories are summed in the main heading(s). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. The abbreviation nsk stands for ‘not specified by kind’ and nec for ‘not elsewhere classified’. A dash (-) means zero.
BIOLOGICAL PRODUCTS, EXCEPT DIAGNOSTICS	8,540.2	industrial, and other uses, nec	1,731.4
Blood and blood derivatives, for human use	1,388.1	Biological veterinary vaccines, bacterins, toxoids, other antigens, and other biological products	917.5
Biological products, blood and blood derivatives, for human use	1,387.7	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, veterinary vaccines, including vaccines against foot-and-mouth disease	585.6
Biological products, diagnostic, blood and blood derivatives, human blood plasma, for human use	953.7	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, bacterins, toxoids, and other antigens, except allergens, for active immunization	65.0
Biological products, except diagnostic, blood and blood derivatives, other blood and blood derivatives or fractions, except those used for passive immunization	434.0	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, other biological products, including veterinary blood derivatives, antitoxins, immune serums, and allergens, except diagnostics	266.9
Blood and blood derivatives, for human use, nsk	0.3	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, biological products for industrial and other uses, except culture media	679.2
Vaccines, toxoids, and antigens, except allergens, for human use	3,015.3	Biological products for industrial and all other miscellaneous uses, non-diagnostic culture media	95.1
Other biologics, except diagnostic, for human use	2,165.2	Biological products, except diagnostic, for veterinary, industrial, and other uses, nec, nsk	39.7
Biological products, except diagnostic, for human use	2,165.2	Biological products, except diagnostics, nsk, total	240.2
Biological products, except diagnostic, other biologics, antitoxins, antivenoms, immune globulins, therapeutic immune serums, etc., for therapeutic use and passive immunization	2,052.4
Biological products, except diagnostic, other biologics, allergenic extracts and other biologics for human use, including poison ivy and oak extracts, except diagnostic allergens	112.8
Biological products, except diagnostic, for veterinary ,

INPUTS AND OUTPUTS FOR BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Compensation of employees	20.9		Pharmaceutical preparations	23.6	Manufg.
Management of companies & enterprises	15.3	Services	Exports of goods & services	12.8	Cap Inv
Biological products (except diagnostic)	13.2	Manufg.	Medicinal & botanical manufacturing	12.0	Manufg.
Wholesale trade	8.6	Trade	Biological products (except diagnostic)	11.2	Manufg.
Scientific research & development services	5.4	Services	Physician, dentist, other health practitioner offices	9.5	Services
Pharmaceutical preparations	2.9	Manufg.	Medical & diagnostic labs & outpatient services	6.2	Services
Medicinal & botanical manufacturing	1.3	Manufg.	In-vitro diagnostic substances	4.7	Manufg.
Management, scientific, & technical consulting	1.2	Services	Change in private inventories	4.6	In House
Advertising & related services	1.2	Services	Cattle	2.0	Agric.
Noncomparable imports	1.1	Foreign	General Federal government services, nondefense	1.9	Fed Govt
Power generation & supply	0.7	Util.	Agriculture & forestry services	1.8	Agric.
Real estate	0.6	Fin/R.E.	Veterinary services	1.5	Services

INPUTS AND OUTPUTS FOR BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING - Continued
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Source: Benchmark Input-Output Accounts for the U.S. Economy, 2002, U.S. Department of Commerce, Washington, D.C., January 2008. The abbreviation nec stands for ‘not elsewhere classified’.
Basic organic chemicals, nec	0.5	Manufg.	Poultry & eggs	1.3	Agric.
Truck transportation	0.4	Util.	Nursing & residential care facilities	0.9	Services
Plastics products, nec	0.4	Manufg.	Amusement parks, arcades, & gambling	0.9	Services
Taxes on production & imports, less subsidies	0.3		Retail trade	0.8	Trade
Lessors of nonfinancial assets	0.3	Fin/R.E.	General S/L govt. services	0.7	S/L Govt
Maintenance/repair of nonresidential structures	0.3	Construct.	Individual & family services	0.7	Services
Services to buildings & dwellings	0.2	Services	Architectural, engineering, & related services	0.5	Services
Business support services	0.2	Services	Community food, housing, relief, & rehabilitation	0.5	Services
Telecommunications	0.2	Services	Museums, historical sites, zoos, & parks	0.5	Services
Warehousing & storage	0.2	Util.	Scientific research & development services	0.4	Services
In-vitro diagnostic substances	0.2	Manufg.	Maintenance/repair of nonresidential structures	0.3	Construct.
Legal services	0.2	Services	Other S/L govt. enterprises	0.2	S/L Govt
Automotive equipment rental & leasing	0.2	Fin/R.E.	Wood containers & pallets	0.1	Manufg.
Employment services	0.2	Services	Hospitals	0.1	Services
Printing	0.2	Manufg.	Personal services, nec	0.1	Services
Automotive repair & maintenance, ex. car washes	0.2	Services
Animal, except poultry, processing	0.2	Manufg.
Chemical products & preparations, nec	0.2	Manufg.
Glass containers	0.2	Manufg.
Commercial & industrial equipment repair/maintenance	0.2	Services
Environmental & other technical consulting services	0.1	Services
Petroleum refineries	0.1	Manufg.
Paperboard containers	0.1	Manufg.
Office administrative services	0.1	Services
Natural gas distribution	0.1	Util.
Data processing, hosting, & related services	0.1	Services
Waste management & remediation services	0.1	Services
Specialized design services	0.1	Services

OCCUPATIONS EMPLOYED BY PHARMACEUTICAL & MEDICINE MANUFACTURING
Occupation	% of Total 2006	Change to 2016	Occupation	% of Total 2006	Change to 2016
Source: Industry-Occupation Matrix, Bureau of Labor Statistics, December 4, 2007. These data are reported based on 4-digit NAICS categories but have been matched to corresponding 6-digit NAICS industry codes. The change reported for each occupation to the year 2016 is a percent of growth or decline as estimated by the Bureau of Labor Statistics. The abbreviation nec stands for ‘not elsewhere classified’.
Packaging & filling machine operators & tenders	7.0	13.4	General & operations managers	1.6	13.4
Chemists	5.2	13.4	Biochemists & biophysicists	1.4	26.0
Mixing & blending machine operators & tenders	3.6	26.0	Machine feeders & offbearers	1.4	13.4
Chemical equipment operators & tenders	3.5	26.0	Packers & packagers, hand	1.4	0.8
Medical scientists, exc epidemiologists	3.4	26.0	Shipping, receiving, & traffic clerks	1.4	21.3
Inspectors, testers, sorters, samplers, & weighers	3.0	18.8	Customer service representatives	1.4	38.6
First-line supervisors/managers of production workers	2.6	26.0	Secretaries, exc legal, medical, & executive	1.3	12.1
Biological technicians	2.5	26.0	Industrial production managers	1.3	26.0
Chemical technicians	2.3	26.0	Managers, nec	1.3	26.0
Maintenance & repair workers, general	2.1	26.0	Production workers, nec	1.2	23.7
Sales representatives, wholesale & manufacturing, tech	2.0	26.0	Office clerks, general	1.2	24.2
Separating, precipitating, & still machine operators	1.9	26.0	Microbiologists	1.1	26.0
Business operation specialists, nec	1.8	38.6	Industrial machinery mechanics	1.1	44.9
Executive secretaries & administrative assistants	1.7	26.0	Accountants & auditors	1.1	26.0
Team assemblers	1.7	26.0	Natural sciences managers	1.1	26.0
Laborers & freight, stock, & material movers, hand	1.6	13.4	Production, planning, & expediting clerks	1.1	26.0

INDUSTRY DATA BY STATE
State	Establishments	Shipments				Employment			Cost as % of Shipments	Investment per Employee ($)
State	Establishments	Total ($ mil)	% of U.S.	Per Establ.	Total Number	% of U.S.	Per Establ.	Wages ($/hour)	Cost as % of Shipments	Investment per Employee ($)
Source: 2002 Economic Census. The states are in descending order of shipments or establishments (if shipment data are missing for the majority). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. States marked with (D) are sorted by number of establishments. A dash (-) indicates that the data element cannot be calculated. Data may not show all states active in the NAICS category. All data available at the time of publication are shown.
North Carolina	12	1,356.0	17.4	113,001.1	2,983	13.1	249	20.49	37.9	43,215
California	45	1,109.9	14.2	24,664.7	4,281	18.7	95	27.49	44.2	21,788
Maryland	13	835.3	10.7	64,253.3	1,029	4.5	79	21.76	7.8	13,920
Massachusetts	15	803.6	10.3	53,572.6	1,334	5.8	89	23.13	9.4	27,343
Iowa	11	444.0	5.7	40,364.3	1,713	7.5	156	12.88	33.4	12,640
Wisconsin	10	198.0	2.5	19,803.1	932	4.1	93	23.36	28.0	10,558
New York	6	132.6	1.7	22,103.0	434	1.9	72	23.19	42.4	8,763
Georgia	8	124.9	1.6	15,614.9	434	1.9	54	15.97	26.9	25,477
Texas	24	88.6	1.1	3,693.0	512	2.2	21	19.15	22.9	10,219
Missouri	10	81.5	1.0	8,149.7	529	2.3	53	18.44	25.9	14,439
Nebraska	7	80.7	1.0	11,532.6	448	2.0	64	18.84	36.0	28,857
Kansas	7	54.9	0.7	7,836.0	257	1.1	37	15.71	31.0	10,354
Minnesota	9	30.7	0.4	3,415.2	172	0.8	19	19.36	31.2	11,390
Maine	7	27.6	0.4	3,940.0	120	0.5	17	13.12	41.6	46,700
Florida	7	20.5	0.3	2,922.7	113	0.5	16	15.46	24.9	3,894